Department of Anaesthesiology and Critical Care Medicine, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany. christoph.sponholz@med.uni-jena.de. Department of Anaesthesiology and Critical Care Medicine, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany. katja.matthes@uni-jena.de. Department of Anaesthesiology and Critical Care Medicine, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany. dina.rupp@uni-jena.de. Department of Anaesthesiology and Critical Care Medicine, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany. wolf.backaus@uni-jena.de. Charité Research Organisation, Berlin, Germany. sebastian.klammt@charite-research.org. Institute of Clinical Chemistry and Laboratory Diagnostics, Jena University Hospital, Jena, Germany. diana.karailieva@med.uni-jena.de. Center for Sepsis Control and Care, Integrated Treatment and Research Center, Jena University Hospital, Jena, Germany. diana.karailieva@med.uni-jena.de. Division of General, Visceral and Vascular Surgery, Jena University Hospital, Jena, Germany. astrid.bauschke@med.uni-jena.de. Division of General, Visceral and Vascular Surgery, Jena University Hospital, Jena, Germany. utz.settmacher@med.uni-jena.de. Department of Medical and Life Sciences, Furtwangen University, Villingen-Schwenningen, Germany. matthias.kohl@hs-furtwangen.de. Center for Sepsis Control and Care, Integrated Treatment and Research Center, Jena University Hospital, Jena, Germany. mgclemen@uncc.edu. The Liver-Biliary-Pancreatic Center, Carolinas Medical Center, Charlotte, NC, USA. mgclemen@uncc.edu. Department of Biology, University of North Carolina at Charlotte, Charlotte, NC, USA. mgclemen@uncc.edu. Division of Nephrology, Department of Medicine, Rostock University Medical Centre, Rostock, Germany. steffen.mitzner@med.uni-rostock.de. Fraunhofer Institute for Cell Therapy and Immunology, Extracorporeal Immunomodulation Project Group, Rostock, Germany. steffen.mitzner@med.uni-rostock.de. Department of Anaesthesiology and Critical Care Medicine, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany. michael.bauer@med.uni-jena.de. Center for Sepsis Control and Care, Integrated Treatment and Research Center, Jena University Hospital, Jena, Germany. michael.bauer@med.uni-jena.de. Department of Anaesthesiology and Critical Care Medicine, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany. andreas.kortgen@med.uni-jena.de. Center for Sepsis Control and Care, Integrated Treatment and Research Center, Jena University Hospital, Jena, Germany. andreas.kortgen@med.uni-jena.de.